abstract：:Interleukin 33 (IL-33) and soluble form of ST2 (sST2) are involved in inflammation. This study aimed to assess the role of serum IL-33 and sST2 in neonates with HCMV infection. The concentration of serum IL-33 and sST2 in 20 patients and 16 healthy controls were measure by enzyme-linked immune-sorbent assay (ELISA). T...

journal_title：Journal of medical virology

authors： Chen Y,Qian J

更新日期：2018-08-01 00:00:00

abstract：:Predictive factors of HCV relapse after treatment with DAAs are poorly understood. In this study, we aimed to assess whether the residual viral load positivity observed during or at the end of treatment (EOT) has an impact on viral outcome. Blood samples were collected from 337 patients with genotypes (GT) 1a, 1b, 2, ...

journal_title：Journal of medical virology

authors： Visco-Comandini U,Lapa D,Lionetti R,Taibi C,Loiacono L,Montalbano M,Capobianchi MR,D'Offizi G,Garbuglia AR

更新日期：2018-07-01 00:00:00

abstract：:B-cells play an important role in defending children against various infections. In view of scare data, we undertook this prospective cohort study to describe B cell compartment in HIV infected children (<5 years of age) and the effect of HAART on B cell subpopulations. HIV infected children (<5 years) from Pediatric ...

journal_title：Journal of medical virology

authors： Singh R,Mukherjee A,Singla M,Vajpayee M,Negi N,Kabra SK,Lodha R,Das BK

更新日期：2018-07-01 00:00:00

abstract：:We report a real-life 3D therapy failure in a patient treated with ombitasvir (OMV)/paritaprevir/ritonavir and dasabuvir without ribavirin (3D-R). He had therapy failure at week 12 after the end of treatment. We detected resistance-associated substitutions (RASs) plus polymorphisms on NS3, NS5A, and NS5B target region...

journal_title：Journal of medical virology

authors： Marascio N,Pavia G,Romeo I,Talarico C,Di Salvo S,Reale M,Marano V,Barreca GS,Fabiani F,Perrotti N,De Siena M,Giancotti F,Gravina T,Alcaro S,Artese A,Torti C,Liberto MC,Focà A

更新日期：2018-07-01 00:00:00

abstract：:Immunological factors, such as cytokines, have been proposed as a cause of changes in the lipid profile of dengue patients. We studied whether serum lipid levels and serum TNF-α levels are associated in a group of dengue patients from an endemic region in the Northwest of Mexico. We found statistically important diffe...

journal_title：Journal of medical virology

authors： Osuna-Ramos JF,Rendón-Aguilar H,Reyes-Ruiz JM,Del Ángel RM,Romero-Utrilla A,Ríos-Burgueño ER,Velarde-Rodriguez I,Velarde-Félix JS

更新日期：2018-06-01 00:00:00

abstract：:Rotavirus vaccines have been available in Japan since 2011. This study conducted to monitor the trend of group A rotavirus (RVA) genotypes 3 years after vaccine introduction. A total of, 539 fecal samples were collected from children with acute gastroenteritis in six regions during July 2014-June 2015. Among them, 178...

journal_title：Journal of medical virology

authors： Khandoker N,Thongprachum A,Takanashi S,Okitsu S,Nishimura S,Kikuta H,Yamamoto A,Sugita K,Baba T,Kobayashi M,Hayakawa S,Mizuguchi M,Ushijima H

更新日期：2018-06-01 00:00:00

abstract：:The study characterized the virological patterns and the resistance-associated substitutions (RASs) in patients with failure to IFN-free regimens enrolled in the real-life setting. All 87 consecutive HCV patients with failed IFN-free regimens, observed at the laboratory of the University of Campania, were enrolled. Al...

journal_title：Journal of medical virology

authors： Starace M,Minichini C,De Pascalis S,Macera M,Occhiello L,Messina V,Sangiovanni V,Adinolfi LE,Claar E,Precone D,Stornaiuolo G,Stanzione M,Ascione T,Caroprese M,Zampino R,Parrilli G,Gentile I,Brancaccio G,Iovinella V,

更新日期：2018-05-01 00:00:00

abstract：:The use of new Direct Acting Antivirals, specific of HCV, has greatly improved the HCV treatment. Most of the DAA are specific of HCV genotypes. Genotyping methods may target different regions of the HCV genome, though only the whole genome sequencing could confirm the correct genotype. The present study describes the...

journal_title：Journal of medical virology

authors： Mourez T,Decroos A,Goria O,Montialoux H,De Oliveira F,Larrat S,Plantier JC,Riachi G

更新日期：2018-05-01 00:00:00

abstract：:G1P[8] rotaviruses are predominant in causing diarrheal infections in humans all over the world. This study reports the analysis of complete genomes of G1P[8] strains, two each recovered from Rotarix™ vaccine recipients and non-recipients hospitalized for acute gastroenteritis in Pune, western India. All four strains ...

journal_title：Journal of medical virology

authors： Pradhan GN,Chitambar SD

更新日期：2018-04-01 00:00:00

abstract：:Influenza A(H1N1)pdm09 virus pandemic struck India in 2009 and continues to cause outbreaks in its post-pandemic phase. Diminutive information is available about influenza A(H1N1)pdm09 from central India. This observational study presents epidemiological and molecular findings for the period of 6 years. Throat swab sa...

journal_title：Journal of medical virology

authors： Sahu M,Singh N,Shukla MK,Potdar VA,Sharma RK,Sahare LK,Ukey MJ,Barde PV

更新日期：2018-03-01 00:00:00

abstract：:The worldwide infection rate of herpesvirus is high, but the detailed prevalence in China, especially the central area, remains unclear. In the present study, the prevalence of herpes simplex virus (HSV), Epstein-Barr virus (EBV), and human cytomegalovirus (HCMV) was investigated in 303 healthy adults in Wuhan, a repr...

journal_title：Journal of medical virology

authors： Wen L,Qiu Y,Cheng S,Jiang X,Ma YP,Fang W,Wang W,Cui J,Ruan Q,Zhao F,Hu F,Luo MH

更新日期：2018-03-01 00:00:00

abstract：:A metagenomic approach based on target independent next-generation sequencing has become a known method for the detection of both known and novel viruses in clinical samples. This study aimed to use the metagenomic sequencing approach to characterize the viral diversity in respiratory samples from patients with respir...

journal_title：Journal of medical virology

authors： Madi N,Al-Nakib W,Mustafa AS,Habibi N

更新日期：2018-03-01 00:00:00

abstract：:Herpes simplex virus (HSV) establishes latency in neurons and recurrent infections in oral mucosa. This prospective study analyzes HSV prevalence in oral mucosal brush samples from men with known human papillomavirus (HPV) status. We hypothesized that HSV-1-infection could facilitate HPV persistence as a cofactor. Thi...

journal_title：Journal of medical virology

authors： Mäki J,Paavilainen H,Kero K,Hukkanen V,Syrjänen S

更新日期：2018-03-01 00:00:00

abstract：:Oral DAA have demonstrated high efficacy as treatment of hepatitis C. However, the presence of resistance-associated substitutions (RAS) at baseline has occasionally been associated with impaired treatment response. Herein, we examined the impact of baseline RAS at the HCV NS5A gene region on treatment response in a r...

journal_title：Journal of medical virology

authors： Carrasco I,Arias A,Benítez-Gutiérrez L,Lledó G,Requena S,Cuesta M,Cuervas-Mons V,de Mendoza C

更新日期：2018-03-01 00:00:00

abstract：:Little information is available on the impact of direct-acting antiviral (DAA) therapy on changes in liver fibrosis and steatosis. Liver stiffness (LS) and controlled attenuation parameter (CAP) values were evaluated using transient elastography. The study subjects were 214 elderly patients infected with HCV genotype ...

journal_title：Journal of medical virology

authors： Ogasawara N,Kobayashi M,Akuta N,Kominami Y,Fujiyama S,Kawamura Y,Sezaki H,Hosaka T,Suzuki F,Saitoh S,Suzuki Y,Arase Y,Ikeda K,Kobayashi M,Kumada H

更新日期：2018-02-01 00:00:00

abstract：:Recent years have seen a high incidence of mumps, which is generally diagnosed based on clinical features, especially parotitis, without laboratory confirmation in Korea. To better understand the epidemiology of mumps in Korean children, we investigated sporadic suspected mumps cases with parotitis. In total, 237 bucc...

journal_title：Journal of medical virology

authors： Kang HJ,Kim SH,Chung JK,Lee SW,Choi SB,Eom HE,Park O,Kim K,Kim SS

更新日期：2018-01-01 00:00:00

abstract：:Does anal HPV viral load explain the difference in anal HPV persistence between HIV-negative and -positive men who have sex with men (MSM)? MSM ≥18 years were recruited in Amsterdam, the Netherlands, in 2010-2011. Anal self-swabs were collected every 6 months and genotyped (SPF10 -PCR-DEIA-LIPA25 -system). HPV16 and H...

journal_title：Journal of medical virology

authors： Marra E,King A,van Logchem E,van der Weele P,Mooij SH,Heijman T,Meijer CJLM,Verhagen DWM,van der Sande MAB,Schim van der Loeff MF

更新日期：2018-01-01 00:00:00

abstract：:The pathogenesis of the Crimean-Congo hemorrhagic fever (CCHF) and the cause of the hemorrhage are not yet fully understood. However, the endothelium plays a key role in the pathogenesis. The purpose of this study was to investigate endothelial dysfunction markers (asymmetrical dimethyl arginine [ADMA], endothelin 1[E...

journal_title：Journal of medical virology

authors： Arslan M,Yilmaz G,Mentese A,Yilmaz H,Karahan SC,Koksal I

更新日期：2017-12-01 00:00:00

abstract：:Chronic HCV infection has emerged as a complex multifaceted disease with manifestations extending beyond the liver. HCV plays a direct role in glucose metabolism leading to both insulin resistance and type 2 diabetes. To evaluate the changes in the glycemic state following Sofosbuvir-based treatment regimens in diabet...

journal_title：Journal of medical virology

authors： Abdel Alem S,Elsharkawy A,Fouad R,Adel E,Abdellatif Z,Musa S,Nagy A,Hussein MS,Yosry A,Esmat G

更新日期：2017-12-01 00:00:00

abstract：:Human cytomegalovirus (HCMV) infection is an important risk factor for atherosclerosis (AS). Numerous studies have been conducted to analyze the association between HCMV infection and risk of AS, but no clear consensus has been reached. So the objective of this paper was aimed to demonstrate the relationship between H...

journal_title：Journal of medical virology

authors： Jia YJ,Liu J,Han FF,Wan ZR,Gong LL,Liu H,Zhang W,Wardell T,Lv YL,Liu LH

更新日期：2017-12-01 00:00:00

abstract：:The aim of the study was to assess whether high-risk pregnant women have a higher prevalence of HEV during the perinatal period. This was a cross-sectional study of 428 patients: Group 1, 127 women with a high-risk pregnancy; Group 2, 97 asymptomatic people with reactivity to HCV or HBV; Group 3, 94 patients with clin...

journal_title：Journal of medical virology

authors： Baptista-González H,Trueba-Gómez R,Rosenfeld-Mann F,Roque-Álvarez E,Méndez-Sánchez N

更新日期：2017-11-01 00:00:00

abstract：:Hantavirus infection during pregnancy can influence both maternal and fetal outcomes. Here, we describe four cases of hemorrhagic fever with renal syndrome (HFRS) in pregnant Chinese women. The HFRS put these women at increased risk for severe illness, despite the patients' symptomologies in the onset phase were simil...

journal_title：Journal of medical virology

authors： Ji F,Zhao W,Liu H,Zheng H,Wang S,He C,Wang W,Zhang R,Bai D,Tian C,Zhao W,Deng H

更新日期：2017-10-01 00:00:00

abstract：:Some international guidelines recommend evaluating the need to confirm positive anti-hepatitis C virus (HCV) antibody screening results by means of a more specific antibody or molecular biology test on the basis of a screening threshold value (such as the sample signal/cut-off ratio) that can predict the positivity of...

journal_title：Journal of medical virology

authors： De Paschale M,Manco MT,Arpino O,Ricucci V,Paganini A,Belvisi L,Cagnin D,Cerulli T,Cianflone A,Agrappi C,Mirri P,Clerici P

更新日期：2017-10-01 00:00:00

abstract：:Epstein-Barr virus (EBV) is an important DNA tumor virus that is associated with approximately 10% of gastric carcinomas and 99% of nasopharyngeal cancers (NPC). DNA methylation and microRNAs (miRNAs) are the most studied epigenetic mechanisms that can prompt disease susceptibility. This study aimed to detect the effe...

journal_title：Journal of medical virology

authors： Zhao Z,Liu W,Liu J,Wang J,Luo B

更新日期：2017-10-01 00:00:00

abstract：:Inosine triphosphatase (ITPA) gene variants can protect against ribavirin (RBV)-induced anemia in patients treated for chronic hepatitis C. The aim of this study was to determine the relationship between genetic variants of ITPA polymorphism, anemia, RBV dose reduction, and treatment response in hepatitis C virus (HCV...

journal_title：Journal of medical virology

authors： El Raziky M,Zayed NA,Abdel Baki A,Mansour SA,Shahin RMH

更新日期：2017-10-01 00:00:00

abstract：:Crimean-Congo hemorrhagic fever infection (CCHF) is a viral zoonosis. The pathogenesis of this disease has not been established so far, however, cytokines account for its progression and outcome. The aim of the present study is to investigate the association between chemokine receptor 5 (CCR5) gene Δ32 mutation and pa...

journal_title：Journal of medical virology

authors： Rustemoglu A,Ekinci D,Nursal AF,Barut S,Duygu F,Günal Ö

更新日期：2017-10-01 00:00:00

abstract：:Flavivirus infections are a serious healthcare concern in tropical and subtropical countries. Although well-established laboratory tests can provide early diagnosis of acute dengue or Zika infections, access to these tests is limited in developing countries, presenting an urgent need to develop simple, rapid, and robu...

journal_title：Journal of medical virology

authors： Bedin F,Boulet L,Voilin E,Theillet G,Rubens A,Rozand C

更新日期：2017-09-01 00:00:00

abstract：:Recruitment of leukocytes by chemokines and chemokine receptors to CNS plays a crucial role in the induction of inflammatory response in HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). In the present study, chemokine and chemokine receptors involved in trafficking of lymphocytes to the CNS were me...

journal_title：Journal of medical virology

authors： Rafatpanah H,Felegari M,Azarpazhooh MR,Vakili R,Rajaei T,Hampson I,Hassanshahi G,Valizadeh N,Gerayli S,Hamid F,Zamanian S,MollaHosseini F,Rezaee SA

更新日期：2017-08-01 00:00:00

abstract：:Although many reports have already shown RSV outbreaks among hemato-oncology patients, genomic studies detecting similar RSV strains prior to an outbreak in the hospital are rare. In 2014, the University of the Ryukyus hospital hemato-oncology unit experienced, and successfully managed, a respiratory syncytial virus (...

journal_title：Journal of medical virology

authors： Nabeya D,Kinjo T,Parrott GL,Uehara A,Motooka D,Nakamura S,Nahar S,Nakachi S,Nakamatsu M,Maeshiro S,Haranaga S,Tateyama M,Tomoyose T,Masuzaki H,Horii T,Fujita J

更新日期：2017-08-01 00:00:00

abstract：:Rhinovirus (RV) is a common respiratory viral infection linked to worsening of chronic respiratory diseases including cystic fibrosis (CF) and asthma. RV was tested by RT-PCR in samples (n = 465) collected from the upper (nasal swab, oropharyngeal suction, and sputum) and lower (bronchoalveolar washings) respiratory t...

journal_title：Journal of medical virology

authors： Stelzer-Braid S,Liu N,Doumit M,D'Cunha R,Belessis Y,Jaffe A,Rawlinson WD

更新日期：2017-08-01 00:00:00

abstract：:Transmission of West Nile virus (WNV) from asymptomatic donors has been reported during blood transfusions and organ transplants in humans. In this work, we aimed to investigate the presence of WNV antibody and WNV RNA in blood donors to evaluate the sero-prevalence of WNV and risk for WNV transmission. One hundred an...

journal_title：Journal of medical virology

authors： Youssef SR,Eissa DG,Abo-Shady RA,Aly Fouad NT,Kattab DK,Fathey H,Abdullaha Elewa AA,Reda DM

更新日期：2017-08-01 00:00:00

abstract：:This study aimed to investigate the characteristics of female high-risk human papillomavirus (HR-HPV) infection in Shaanxi province of China. A total of 14 111 women were enrolled for HPV genotyping test, and a cytology, and/or cervix biopsy were performed in partial women. Of these women, the HPV infection rate was 3...

journal_title：Journal of medical virology

authors： Cao D,Zhang S,Zhang Q,Wei X,Zhao M,Ma Q,Li Y,Wang L,Pei M,Yang T,Zhao J,Yang X

更新日期：2017-07-01 00:00:00

abstract：:It is need for development of new means against influenza virus due to the lack of efficacy of available therapeutic strategies. In previous research, 1,8-cineol exert its inhibition of nuclear factor (NF)-κB, the main regulator of cytokine and chemokine production in influenza, and anti-inflammatory activity. These f...

journal_title：Journal of medical virology

authors： Lai YN,Li Y,Fu LC,Zhao F,Liu N,Zhang FX,Xu PP

更新日期：2017-07-01 00:00:00

abstract：:The paper describes the results of preclinical testing of the preparation "Vaccine allantoic split-virus inactivated against seasonal influenza." Acute toxicity and local irritating effect, anaphylactic reactions to different antigens (vaccine and ovalbumin), delayed-type hypersensitivity to ram erythrocytes, humoral ...

journal_title：Journal of medical virology

authors： Sarsenbayeva G,Volgin Y,Kassenov M,Issagulov T,Bogdanov N,Nurpeisova A,Sagymbay A,Abitay R,Stukova M,Sansyzbay A,Khairullin B

更新日期：2017-07-01 00:00:00

abstract：:According to the Joint National Programme on HIV/AIDS (UNAIDS), the northeastern region of India has the highest HIV prevalence in the country. This study was conducted to determine the current HIV-1 molecular epidemiology of Manipur, a state in northeast India. Blood samples from HIV-1 seropositive subjects were coll...

journal_title：Journal of medical virology

authors： Sharma AL,Singh TR,Devi KR,Singh LS

更新日期：2017-06-01 00:00:00

abstract：:Human papillomavirus (HPV) is a carcinogenic agent responsible for tumor development in many sexually involved tissues. We present a survey on the prevalence of HPV infection in a risk population for sexually transmitted infections (STIs). The studied population was formed by 125 STI clinic attendees, who took part in...

journal_title：Journal of medical virology

authors： Ciccarese G,Herzum A,Rebora A,Drago F

更新日期：2017-06-01 00:00:00

abstract：:Currently, data examining nationally representative prevalence and trends of HBV or HCV among specific subgroups of pregnant women in the US are unavailable. We conducted a cross-sectional analysis of hospitalizations for liveborn singleton deliveries from 1998 to 2011 using data from the Nationwide Inpatient Sample. ...

journal_title：Journal of medical virology

authors： Salemi JL,Spooner KK,Mejia de Grubb MC,Aggarwal A,Matas JL,Salihu HM

更新日期：2017-06-01 00:00:00

abstract：:Human T-cell lymphotropic virus 1 (HTLV-1) is associated with two progressive diseases: HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) and adult T-cell leukemia/lymphoma (ATLL). Although HTLV-1 proviral load (PVL) has been introduced as a risk factor for these diseases' progression, it is not suff...

journal_title：Journal of medical virology

authors： Mozhgani SH,Jaberi N,Rezaee SA,Bustani R,Jazayeri SM,Akbarin MM,Milani S,Tarokhian H,Norouzi M

更新日期：2017-06-01 00:00:00

abstract：:Dengue, caused by any of the four types of Dengue virus (DENV) is the most important arbovirus in the world. In this study we performed a molecular surveillance of dengue during the greatest dengue outbreak that took place in Divinópolis, Minas Gerais state, Southeast Brazil, in 2013. Samples from 100 patients with cl...

journal_title：Journal of medical virology

authors： Dutra KR,Drumond BP,de Rezende IM,Nogueira ML,de Oliveira Lopes D,Calzavara Silva CE,Siqueira Ferreira JM,Dos Santos LL

更新日期：2017-06-01 00:00:00

abstract：:Several viruses are associated with gastroenteritis in infants. This pilot study, nested within a larger community-based project of early childhood infections, collected daily symptom data and 511 weekly stool samples from five healthy, fully vaccinated, term infants from birth until their second birthday. Real-time P...

journal_title：Journal of medical virology

authors： Ye S,Whiley DM,Ware RS,Sloots TP,Kirkwood CD,Grimwood K,Lambert SB

更新日期：2017-05-01 00:00:00